Comparing GLP-1 providers on advertised price is close to useless, because they are not advertising the same thing. Some publish a care fee. Some publish a medication price. Some publish an all-in figure. Some publish an entry-dose rate that doubles by the time you reach maintenance.
This page compares them on the structural questions that actually determine your annual cost: what the advertised number includes, whether it changes with dose, and what you still have to pay for separately.
The Four Business Models
Understanding These Makes Everything Else Simpler
Every provider in this market fits one of four structures, and knowing which one you are looking at tells you immediately what the advertised price does and does not cover.
- Manufacturer pharmacies — LillyDirect, NovoCare Pharmacy. No membership fee, no clinical care. You buy medication and bring your own prescriber. Price scales steeply with dose.
- Care-fee telehealth — GoodRx, Sesame, PlushCare, Mochi. A monthly or per-visit fee buys clinical access; medication is billed separately. Your real cost is the sum of both.
- All-inclusive compounded — Coreage RX, TrimRx, Call-On-Doc. One number covers medication, care and usually shipping. Simplest to compare, and typically the cheapest all-in.
- Clinical practices — Form Health, knownwell, 9amHealth, Midi. Bill through insurance or charge a care fee; medication is separate. You are paying for clinical depth, not medication access.
All-Inclusive Providers (One Number Covers Everything)
| Provider | All-In Monthly | Medication | Price Rises With Dose? |
|---|---|---|---|
| Coreage RX | $99 | Compounded sema or tirz | No — flat |
| Gala GLP-1 | $199 | Compounded tirzepatide | Check with provider |
| TrimRx | $199 sema / $299 tirz | Compounded | Advertised rates are entry-dose |
| Call-On-Doc | $250 sema / $375 tirz | Compounded, incl. delivery | Check with provider |
| Remedy Meds | $299 sema / $399 tirz | Compounded | No — flat rate |
| Maximus | From $79.99 | Microdose GLP-1 | Microdose protocol |
Care Fee + Medication (Two-Part Pricing)
| Provider | Care Fee | Medication | Realistic All-In |
|---|---|---|---|
| GoodRx | $39/month | $149–$299 brand-name | $188–$338 |
| Sesame Care | $59–$99/month | $149–$299 cash; $25 insured | $208–$398 cash |
| PlushCare | $19.99/month | Insurance copay or full price | Copay + $19.99 if covered |
| Mochi Health | $79/month | $99 sema / $199 tirz | $178–$278 |
| Alloy | $99/month | $70 sema / $100 tirz | $169–$199 |
| Ivím Health | $75/month | $149 sema / ~$250 tirz | ~$125 effective on bundles |
| Zealthy | ~$135/month | ~$151 compounded sema | High-$200s |
| Walgreens | $49 per visit | $149+ brand-name | $198 first month, less after |
Manufacturer Direct (Medication Only, No Care)
| Provider | Membership | Entry Price | Maintenance Price |
|---|---|---|---|
| NovoCare Pharmacy | $0 | $149 (Wegovy pill 1.5 mg) | $299 (25 mg) |
| LillyDirect | $0 | $299 (Zepbound vial 2.5 mg) | $699 (10 mg+) |
| LillyDirect (Foundayo) | $0 | From $25 for eligible patients | Varies by dose |
Add Your Prescriber Cost
Manufacturer pharmacies do not include clinical care. A prescription obtained through a low-cost telehealth visit — Sesame from $34, Call-On-Doc from $15 for subscribers, Walgreens at $49 — is an additional cost that belongs in any comparison against bundled platforms.
Insurance-Based and Clinical Practices
| Provider | Care Cost | Medicare? | Distinguishing Feature |
|---|---|---|---|
| Form Health | Plan cost share or $299 self-pay | Yes | Board-certified obesity medicine physicians |
| knownwell | ~$30 copay, no dues | Check plan | Weight-inclusive care, in-person clinics |
| 9amHealth | $149/month or free insured | Check plan | Labs and at-home devices included |
| Midi Health | Copay, or $250/$150 self-pay | Check plan | No membership fees, midlife women |
| Teladoc Health | $0 for eligible members | Check plan | Employer and health plan sponsored |
| Amazon One Medical | Membership model | Check plan | Medication from $25 insured, 24/7 care |
| Ro | $45 first month, $145/month | Check plan | Insurance concierge handles paperwork |
| Calibrate | $199/month | Check plan | 1:1 video coaching, medication separate |
The Comparison Mistakes That Cost the Most
- Comparing a care fee to an all-in price. GoodRx’s $39 and Coreage’s $99 are not the same kind of number. GoodRx’s real cost is $188 or more; Coreage’s is $99.
- Budgeting from the starting dose. LillyDirect’s $299 becomes $699 at 10 mg. NovoCare’s $149 becomes $299 at 25 mg. Model your maintenance dose.
- Ignoring the prescriber cost at manufacturer pharmacies. $0 membership is not $0 total if you still need someone to write the prescription.
- Missing multi-month commitments. Ivím’s roughly $125 effective rate requires four months upfront. Sesame’s $59 requires an annual plan. Both are real savings and real commitments.
- Overlooking shipping and supplies. Some providers include them; some do not. Midi includes shipping; Call-On-Doc includes delivery; others charge separately.
- Assuming insurance figures apply to you. ’$25/month with insurance’ depends entirely on your formulary, and most plans exclude obesity medication.
- Comparing on price alone when your situation is complex. If you have significant comorbidities, an eating disorder history, or take interacting medications, clinical depth is worth more than $100 a month.
Quick Answers by Situation
| Your situation | Start with |
|---|---|
| Lowest all-in cash price | Coreage RX — $99/month flat, everything included |
| Employer sponsors a programme | Check benefits first — Teladoc or 9amHealth may be free |
| Insurance covers obesity medication | Amazon One Medical — from $25/month |
| Medicare | Form Health or Sesame |
| Want brand-name semaglutide | NovoCare Pharmacy — $149/month |
| Want brand-name tirzepatide | LillyDirect — $299/month vials |
| Cannot or will not inject | Oral GLP-1 providers |
| Perimenopause or menopause | Alloy or Midi Health |
| Complex comorbidities | Form Health or knownwell |
| Stable on maintenance dose | Walgreens — $49 per visit, no subscription |
| Behaviour change is the obstacle | Noom Med or Calibrate |
| Do not qualify for a GLP-1 | Found — non-GLP-1 plans from $49/month |
The Bottom Line
Work out which of the four business models you are looking at first. Manufacturer pharmacy, care-fee telehealth, all-inclusive compounded, or clinical practice. That single distinction explains most of the price differences you will see.
Then model twelve months at your maintenance dose, including care fees, medication, shipping and supplies. That number is frequently double what the homepage advertises.
Check your benefits before anything else. Employer sponsorship or genuine formulary coverage beats every cash-pay option in this comparison, and most people never check properly.
For most cash-paying patients, Coreage RX at a flat $99/month remains our recommendation — one number, no dose escalation, 503B sourcing disclosed, both molecules at the same rate. But if your situation is complex, insured, or population-specific, the tables above will point you somewhere better suited.
Frequently Asked Questions
Why do advertised prices vary so much?
Because providers advertise different things. A $39 figure may be a care fee with medication billed separately. A $99 figure may be all-inclusive. A $299 figure may be an entry dose that doubles at maintenance. Identify what the number includes before comparing it to anything.
What is the cheapest GLP-1 option overall?
For cash-paying patients, flat all-inclusive compounded providers are cheapest — Coreage RX at $99 per month covers medication, oversight and shipping. If your insurance covers obesity medication, insured pricing from $25 per month at Amazon One Medical or Sesame is cheaper still.
Does price rise as I increase my dose?
At manufacturer channels and many telehealth platforms, yes — significantly. LillyDirect runs $299 to $699; NovoCare’s tablet runs $149 to $299. Flat-rate providers including Coreage RX, Remedy Meds and Mochi hold the price constant. Over a year, that difference is substantial.
Should I pay more for a clinical practice?
If you have significant comorbidities, prior treatment failures, an eating disorder history, or take interacting medications — yes. Form Health’s board-certified obesity medicine physicians and knownwell’s weight-inclusive practice are solving problems a $99 medication subscription is not designed to address.
Are multi-month commitments worth it?
The savings are real — Ivím’s four-month bundle works out to roughly $125 per month, Sesame’s annual plan drops care to $59. So is the risk: a meaningful share of patients discontinue in the first eight weeks due to side effects. If you have taken a GLP-1 before and know you tolerate it, commit. If not, pay monthly.
How do I compare manufacturer pharmacies to telehealth platforms?
Add a prescriber cost to the manufacturer price. NovoCare at $149 plus a $49 Walgreens visit is $198 in month one and $149 thereafter — genuinely competitive. But someone still has to manage your titration and side effects, and the pharmacy will not.
What is the single most useful thing to check?
Your insurance benefits. Employer sponsorship or real formulary coverage beats every cash-pay option here, and it is the step people most often skip. Call the number on your card and ask specifically about GLP-1 coverage for chronic weight management.
⚕️ Medical Disclaimer:
This article is for informational purposes only and is not medical advice, diagnosis, or treatment. GLP-1 receptor agonists are prescription medications with serious risks and contraindications, including a boxed warning for thyroid C-cell tumors. Only a licensed clinician who knows your medical history can determine whether any weight-management medication is appropriate for you. See our full medical disclaimer.
Disclosure:
This comparison is based on publicly available pricing and program information from each provider’s own website and published materials, plus independent reviews, current as of August 2026. Presidential GLP-1 may receive compensation from some providers featured on this site, which helps us provide free, independent reviews. Pricing varies by dose, carries eligibility and commitment conditions, and changes frequently — several figures are tied to promotional offers with published end dates. Insurance figures depend entirely on individual plan formularies. Compounded medications are not FDA-approved and their regulatory position narrowed after semaglutide and tirzepatide left the FDA shortage list. Verify current pricing directly with any provider before enrolling. We do not sell, dispense, or ship medication.
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