Semaglutide (brand names Wegovy for weight loss, Ozempic for diabetes) is a GLP-1 receptor agonist that clinical trials show produces 15-17% average weight loss over 68 weeks. But brand-name versions cost $1,300+/month without insurance, making them unaffordable for most Americans.
This guide ranks the cheapest compounded semaglutide providers that maintain legitimate quality standards. We filter out dangerous low-cost options while identifying affordable alternatives that deliver the same active ingredient at 85-95% lower cost. Affordable semaglutide doesn't have to mean compromising your health.
Understanding Affordable Semaglutide
What Is Compounded Semaglutide?
Compounded semaglutide uses the same active pharmaceutical ingredient as Wegovy/Ozempic but is prepared by licensed pharmacies rather than Novo Nordisk. It's not FDA-approved but is legal when properly compounded. Clinical effect is identical—the difference is manufacturing and cost.
Why Compounded Is 85-95% Cheaper
Brand-name Wegovy: $1,300+/month. Compounded semaglutide: $99-350/month. The massive price difference reflects pharmaceutical company R&D costs, marketing, and profit margins versus pharmacy compounding costs. The active ingredient is the same; the business model is different.
Safety Considerations
Legitimate compounded semaglutide from FDA-registered 503A or 503B pharmacies with physician oversight is safe. Avoid: providers under $75/month (likely substandard), no physician consultation, unclear pharmacy sourcing, offshore medication, or "semaglutide alternatives" that aren't real semaglutide.
How We Evaluated Cheap Semaglutide Providers
💵 Monthly Cost
Total monthly price including medication, physician consults, shipping, and all fees. No hidden costs.
🏥 Pharmacy Quality
FDA-registered 503A or 503B pharmacies, sterile compounding practices, third-party testing, quality assurance.
👨⚕️ Medical Oversight
Licensed physician (MD/DO) or nurse practitioner evaluation, safety screening, contraindication review, ongoing monitoring.
📦 Included Services
Free shipping, syringes/needles, sharps container, alcohol swabs, provider support access.
🎯 Value Assessment
Quality delivered per dollar spent. Cheapest isn't always best if corners are cut on safety.
🔄 Flexibility
Month-to-month vs prepayment, cancel anytime vs commitment, upfront costs.
Coreage RX
Coreage RX offers the cheapest legitimate compounded semaglutide we've found at $99/month all-inclusive—92% less than brand-name Wegovy ($1,300+/month). This isn't a promotional rate or first-month special; it's the standard ongoing price with zero hidden fees.
Despite the budget pricing, Coreage maintains premium quality standards with 503B outsourcing facility sourcing (highest tier for compounded medications), board-certified physician oversight, and temperature-controlled shipping. The $99 includes medication, medical consultation, syringes, shipping, and unlimited provider messaging.
Month-to-month with no prepayment or long-term commitment. Cancel anytime without penalty. For patients who can't afford $1,300/month Wegovy or whose insurance won't cover it, Coreage makes semaglutide weight loss accessible without sacrificing safety or clinical quality.
✓ Why It's #1:
- • $99/month (cheapest we've found)
- • 503B pharmacy (highest quality tier)
- • All-inclusive (no extra fees)
- • Board-certified physician oversight
- • Unlimited messaging support
- • Month-to-month (no commitment)
- • Free temperature-controlled shipping
- • 92% cheaper than Wegovy
⚠️ Considerations:
- • Compounded (not FDA-approved Wegovy)
- • Cash-pay only (no insurance)
- • Weekly self-injection required
- • Newer brand vs established names
Hims
Hims offers compounded semaglutide at $199/month—still 85% cheaper than Wegovy ($1,300+). The catch: requires 6-month prepayment ($1,194 upfront). For patients who can afford the initial investment, Hims delivers competitive pricing from an established, publicly-traded telehealth brand (NYSE: HIMS).
FSA/HSA eligible, polished digital platform, reliable customer support, and Novo Nordisk partnership for brand-name Wegovy access (with insurance). The prepayment model reduces month-to-month flexibility but the per-month price is solid for a mainstream brand with 1M+ customers.
Henry Meds
Henry Meds provides compounded semaglutide at $297/month with exceptional pricing transparency—no consultation fees, no membership fees, no shipping charges, no surprise costs. What you see is exactly what you pay. The medication price includes board-certified physician oversight, unlimited messaging, and all injection supplies.
While more expensive than #1-2, Henry Meds appeals to patients burned by hidden fees at other providers. Reputation for excellent customer service, straightforward communication, and month-to-month flexibility (no prepayment). Still 77% cheaper than brand-name Wegovy while maintaining quality standards.
Ro
Ro offers both compounded semaglutide ($300+/month) and brand-name Wegovy (insurance-dependent pricing). The dual approach means if you have insurance that covers Wegovy, Ro handles the prior authorization and pharmacy coordination. If not, they seamlessly switch you to compounded at affordable rates.
The flexibility appeals to patients with uncertain insurance coverage or those who may gain coverage later. Established platform, comprehensive weight loss program integration, coaching support included. Higher pricing than top 3 but the brand-name pathway adds value for insured patients.
Mochi Health
Mochi Health charges $338/month total ($79 membership + $259 semaglutide) with unlimited access to both doctors and registered dietitians. The two-part pricing is higher than medication-only competitors, but the comprehensive coaching helps maximize weight loss results beyond medication alone.
Mobile app for tracking, meal logging, progress monitoring, and provider messaging. Clinical data shows behavior change + medication produces 40-54% better outcomes than medication alone. If you want the full weight loss program (not just cheap semaglutide), Mochi's integrated approach justifies the premium pricing.
Quick Comparison Table
| Provider | Rating | Monthly Cost | Commitment | Best For |
|---|---|---|---|---|
| Coreage RX | ★★★★★ | $99 | Month-to-month | Cheapest option |
| Hims | ★★★★☆ | $199 | 6-month prepay | Established brand |
| Henry Meds | ★★★★☆ | $297 | Month-to-month | Transparency |
| Ro | ★★★★☆ | $300+ | Month-to-month | Brand-name access |
| Mochi Health | ★★★★☆ | $338 total | Month-to-month | Includes coaching |
Our Recommendation
For the cheapest semaglutide, Coreage RX at $99/month is unbeatable—92% less than brand-name Wegovy ($1,300+/month). This is the lowest price we've found from a provider meeting legitimate safety standards (503B pharmacy, licensed physicians, proper medical oversight).
Month-to-month with no prepayment, hidden fees, or long-term commitment makes Coreage accessible to budget-conscious patients. The clinical effect is identical to Wegovy—the active ingredient (semaglutide) is the same; only the manufacturing and price are different.
Alternative recommendations based on priorities:
- Can prepay 6 months: Hims ($199/mo with $1,194 upfront, NYSE-listed company)
- Transparent pricing: Henry Meds ($297/mo, zero hidden fees, great support)
- Insurance option: Ro ($300+/mo compounded, brand-name Wegovy if insured)
- Want coaching included: Mochi Health ($338/mo with unlimited dietitian access)
Critical warning: Avoid semaglutide providers charging under $75/month, offering unclear pharmacy sourcing, no physician consultation, offshore medication, or "semaglutide alternatives." Saving money isn't worth risking your health with substandard compounding or non-sterile medication.
Compare All Semaglutide Providers
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