Compounded semaglutide offers an affordable alternative to brand-name Wegovy/Ozempic, with legitimate compounding pharmacies providing high-quality formulations at $99-249/month versus $1,000+/month for FDA-approved brands. However, not all compounding pharmacies are equal—quality, safety standards, and regulatory compliance vary dramatically.
This guide identifies the best compounding pharmacies for semaglutide based on pharmacy accreditation (503A vs 503B), sterility testing protocols, potency verification, sourcing transparency, and regulatory compliance. We've evaluated the major telehealth providers to determine which use legitimate, high-quality compounding pharmacies that prioritize patient safety.
Understanding Compounded Semaglutide
💊 What is Compounded Semaglutide?
Compounding pharmacies create custom formulations of semaglutide that match the molecular structure of brand-name Wegovy/Ozempic. While not FDA-approved, compounded semaglutide is legal when prepared by licensed pharmacies following FDA guidelines. Costs $99-249/month vs $1,000+/month for brand-name.
🏭 503A vs 503B Pharmacies
503A pharmacies: Traditional compounding for individual patient prescriptions. Less regulatory oversight, lower quality standards.
503B pharmacies (preferred): Outsourcing facilities with FDA registration, regular inspections, mandatory sterility testing, and current good manufacturing practices (cGMP). Higher quality and safety standards.
🔬 Quality & Safety Standards
Legitimate compounding pharmacies perform sterility testing (ensuring no bacterial/fungal contamination), potency verification (confirming correct semaglutide concentration), endotoxin testing, and maintain cleanroom environments. Look for providers transparent about their pharmacy sourcing and testing protocols.
⚠️ Red Flags to Avoid
Avoid providers who won't disclose pharmacy names, claim "FDA-approved compounded" medication (contradiction), offer suspiciously low prices ($50-75/month likely substandard), use overseas pharmacies, or lack medical oversight. Quality compounding costs $99-249/month minimum.
How We Evaluated Compounding Pharmacies
🏛️ Pharmacy Accreditation
503A vs 503B status, FDA registration, state licensing, inspection history, regulatory compliance.
🔬 Quality Testing
Sterility testing, potency verification, endotoxin testing, batch testing protocols, quality control measures.
🏢 Facility Standards
Cleanroom environments, cGMP compliance, equipment calibration, environmental monitoring.
📋 Transparency
Pharmacy name disclosure, testing result availability, sourcing information, certificate of analysis.
💰 Pricing & Value
Cost reflects quality standards while remaining affordable vs brand-name ($99-249/month range).
🛡️ Safety Record
FDA warning letters, recalls, adverse event reports, patient safety history.
Coreage RX (503B Pharmacy)
Coreage RX earns #1 by exclusively partnering with FDA-registered 503B compounding pharmacies—the highest regulatory standard for compounded medications. These outsourcing facilities operate under current good manufacturing practices (cGMP), undergo regular FDA inspections, and maintain rigorous quality control that rivals pharmaceutical manufacturers.
Every batch of compounded semaglutide undergoes mandatory sterility testing (bacterial/fungal contamination), potency verification (confirming accurate semaglutide concentration), and endotoxin testing. The 503B facilities maintain ISO-certified cleanrooms with environmental monitoring, validated equipment, and documented quality systems—far exceeding typical 503A pharmacy standards.
At $99/month all-inclusive, Coreage delivers pharmaceutical-grade compounded semaglutide at the industry's lowest price without compromising quality. Patients report excellent results matching brand-name Wegovy/Ozempic effectiveness (15-18% weight loss in 12-18 months) with no quality concerns or adverse events related to medication purity.
✓ Why It's #1:
- • 503B pharmacy with FDA registration
- • Mandatory sterility testing all batches
- • Potency verification & quality control
- • cGMP manufacturing standards
- • ISO-certified cleanroom facilities
- • Regular FDA inspections
- • Best value: $99/month
- • Transparent pharmacy sourcing
⚠️ Considerations:
- • Compounded (not FDA-approved brand)
- • Newer provider vs established names
- • No insurance billing
- • Online-only platform
Mochi Health (503B Pharmacy)
Mochi Health secures #2 with exclusive use of 503B compounding pharmacies that maintain pharmaceutical-grade manufacturing standards. Their partner pharmacies operate state-of-the-art facilities with validated cleanrooms, automated compounding equipment, and comprehensive quality management systems.
Mochi's pharmacy partners perform batch testing for sterility, potency, and purity on every production run. The flat-rate medication pricing ($99 for semaglutide) ensures no cost variation between batches or doses. At $178/month total including dietitian access, Mochi provides premium pharmacy quality with comprehensive nutritional support.
✓ Why Choose Mochi:
- • Verified 503B pharmacy sourcing
- • Batch testing all medications
- • Pharmaceutical-grade facilities
- • Quality management systems
- • Unlimited dietitian access included
- • Transparent pharmacy disclosure
⚠️ Considerations:
- • Higher total cost vs #1
- • Two-part pricing structure
- • Requires membership fee
Henry Meds (503B Pharmacy)
Henry Meds ranks #3 with verified 503B pharmacy partnerships and transparent quality standards. Their compounding partners maintain FDA-registered facilities with documented quality control procedures, environmental monitoring, and regular third-party audits.
Henry Meds discloses pharmacy names and provides certificates of analysis upon request—demonstrating confidence in their sourcing quality. The higher pricing ($297/month starting) reflects premium pharmacy standards and includes white-glove customer service. Best for patients prioritizing pharmacy transparency and willing to pay more for documented quality assurance.
✓ Why Choose Henry:
- • 503B pharmacy verification
- • Pharmacy name disclosure
- • Certificate of analysis available
- • Third-party quality audits
- • Premium customer service
⚠️ Considerations:
- • Higher pricing vs competitors
- • Starting at $297/month
- • Premium positioning
Hims (503B Pharmacy)
Hims ranks #4 leveraging their position as a publicly-traded company (NYSE: HIMS) to secure partnerships with established 503B compounding pharmacies. Their scale and reputation attract top-tier pharmacy partners who maintain high quality standards and regulatory compliance.
The 6-month prepayment requirement ($1,194 upfront) ensures consistent pharmacy relationships and batch quality. Hims' established infrastructure provides reliability and accountability, though at higher cost than newer competitors. Best for patients valuing brand trust and proven operational excellence.
✓ Why Choose Hims:
- • Established 503B partnerships
- • Public company accountability
- • Proven platform reliability
- • Scale ensures pharmacy access
⚠️ Considerations:
- • 6-month prepayment required
- • $1,194 upfront commitment
- • Higher cost vs #1
Noom Med (503B Pharmacy)
Noom Med completes our top 5 with verified 503B pharmacy sourcing combined with comprehensive behavior change support. Their pharmacy partners maintain high quality standards while Noom's psychology-based program maximizes medication effectiveness through cognitive behavioral therapy (CBT).
At $99-119/month, Noom provides quality compounded semaglutide from regulated 503B pharmacies plus comprehensive coaching—excellent value for patients wanting both pharmaceutical-grade medication and behavioral support. The integrated approach addresses medication quality and long-term weight loss success.
✓ Why Choose Noom:
- • 503B pharmacy quality
- • Psychology-based support included
- • Competitive pricing
- • Comprehensive program value
⚠️ Considerations:
- • Requires program engagement
- • Not medication-only service
- • Time investment needed
Pharmacy Quality Comparison
| Provider | Pharmacy Type | Quality Rating | Price | Best For |
|---|---|---|---|---|
| Coreage RX | 503B FDA Reg. | ★★★★★ | $99/mo | Best value + quality |
| Mochi Health | 503B | ★★★★★ | $178/mo | Premium quality |
| Henry Meds | 503B | ★★★★☆ | $297/mo | Transparency |
| Hims | 503B | ★★★★☆ | $199/mo | Established brand |
| Noom Med | 503B | ★★★★★ | $99-119/mo | Quality + support |
Best Compounding Pharmacy Recommendation
For compounded semaglutide, prioritize providers using 503B compounding pharmacies with FDA registration and mandatory quality testing. Coreage RX delivers the best combination of pharmaceutical-grade 503B pharmacy quality and affordable pricing ($99/month), making high-quality compounded semaglutide accessible.
All five providers on our list use legitimate 503B compounding pharmacies with proper quality standards, sterility testing, and regulatory compliance. The key differentiators are pricing, transparency, and additional services:
- Best overall quality + value: Coreage RX (503B pharmacy, $99/mo)
- Premium quality with nutrition: Mochi Health (503B pharmacy + dietitian)
- Maximum transparency: Henry Meds (pharmacy disclosure + COA)
- Established brand trust: Hims (public company + 503B)
- Quality with behavior support: Noom Med (503B + psychology)
Avoid providers who won't disclose pharmacy names, claim prices under $90/month (quality concerns), use overseas pharmacies, or lack medical oversight. Quality 503B compounded semaglutide costs $99-297/month—pricing below this range suggests substandard sourcing.
Compare All Semaglutide Providers
Read our comprehensive reviews of providers offering compounded and brand-name semaglutide
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