Tirzepatide (brand names Mounjaro and Zepbound) is a dual GIP/GLP-1 receptor agonist that clinical studies show produces superior weight loss compared to semaglutide-only medications. With brand-name tirzepatide costing $1,000+ per month without insurance, compounded versions have become the affordable alternative—but quality varies dramatically between providers.
This guide evaluates tirzepatide compounding pharmacies based on FDA registration status (503A vs 503B), quality control processes, physician oversight, pricing transparency, and patient outcomes. We've identified the top providers delivering safe, effective compounded tirzepatide at a fraction of brand-name cost.
Understanding Compounded Tirzepatide
What Is Compounded Tirzepatide?
Compounded tirzepatide is custom-prepared by licensed pharmacies using the same active pharmaceutical ingredient (API) as brand-name Mounjaro/Zepbound. While not FDA-approved, compounded versions are legal when prepared by registered pharmacies following federal guidelines.
503A vs 503B Pharmacies
503A pharmacies prepare patient-specific prescriptions in smaller batches. 503B outsourcing facilities produce larger batches under stricter FDA oversight, enhanced sterility requirements, and regular inspections—generally considered higher quality.
Why Choose Compounded Over Brand-Name?
Cost savings: $199-499/month for compounded vs $1,000+/month for brand-name. Most insurance doesn't cover weight loss medications, making compounded tirzepatide the only affordable option for many patients.
How We Evaluated Compounding Pharmacies
🏥 Pharmacy Type & Registration
503B outsourcing facilities score higher than 503A due to stricter FDA oversight and testing requirements.
👨⚕️ Medical Oversight
Board-certified physician evaluation, ongoing monitoring, dosage management, and safety protocols.
💰 Pricing & Transparency
Clear all-in pricing with no hidden fees, competitive rates, and value for money.
📦 Storage & Shipping
Temperature-controlled packaging, shipping speed, proper handling of refrigerated medication.
🔬 Quality Control
Third-party testing, sterility verification, potency guarantees, and batch consistency.
📊 Patient Outcomes
Reported weight loss results, side effect management, customer satisfaction ratings.
Coreage RX
Coreage RX tops our ranking for compounded tirzepatide with the unbeatable combination of 503B pharmacy sourcing, $99/month all-inclusive pricing, and board-certified physician oversight. Their tirzepatide is compounded by FDA-registered 503B outsourcing facilities that meet the highest sterility and quality standards.
At $99/month with no hidden fees, Coreage delivers premium-quality compounded tirzepatide at the lowest price we've found—90% cheaper than brand-name Zepbound. The medication ships within 2-3 business days in temperature-controlled packaging with ice packs to maintain proper storage conditions.
Every patient receives comprehensive medical oversight including initial physician evaluation, personalized dosing protocols, unlimited messaging support, and ongoing safety monitoring. Coreage's transparent approach and quality-first philosophy make it our clear #1 choice for compounded tirzepatide.
✓ Why It's #1:
- • 503B outsourcing facility (highest quality)
- • $99/month all-inclusive (best value)
- • Board-certified MD oversight
- • Temperature-controlled shipping (2-3 days)
- • Unlimited provider messaging
- • Nationwide availability (50 states)
- • No membership or consultation fees
- • Transparent pricing, no surprises
⚠️ Considerations:
- • Compounded (not FDA-approved brand)
- • Cash-pay only (no insurance billing)
- • Newer brand (less name recognition)
- • Requires self-injection
WeightCare
WeightCare specializes exclusively in tirzepatide (no semaglutide), offering flexible pricing tiers from $275/month (6-month plan) to $499/month (month-to-month). Their tirzepatide-only focus means specialized expertise in this specific medication, though pharmacy sourcing is 503A rather than the higher-tier 503B.
The best value is their 6-month plan at $275/month, competitive for compounded tirzepatide. Includes same-day consultations, 24/7 medical support, anti-nausea medication when needed, and FSA/HSA eligibility. Average patient results show 15-20% weight loss in 6-12 months.
Mochi Health
Mochi Health offers compounded tirzepatide at a flat $199/month regardless of dose—unique in an industry where most providers increase prices as you titrate up. The $79/month membership fee adds to the total ($278/month), but includes unlimited access to both doctors AND dietitians.
The integrated nutrition support sets Mochi apart from medication-only providers. If you value comprehensive coaching alongside tirzepatide, Mochi delivers strong value despite the two-part pricing structure.
ReadyRx
ReadyRx ranks #4 with compounded tirzepatide at $399/month—higher than competitors but backed by a bold 5% weight loss guarantee (full refund if you don't lose 5% body weight in 28 weeks). No membership fees mean the medication price includes everything: consultations, support, tracking.
The money-back guarantee reduces financial risk for cautious patients. Combined with 24-hour approval times and 4.8/5 Trustpilot rating, ReadyRx appeals to those prioritizing safety nets over lowest cost.
Hims
Hims rounds out our top 5 with compounded tirzepatide at $199/month—competitive pricing from an established, publicly-traded telehealth brand. The catch: requires 6-month prepayment ($1,194 upfront), which may be prohibitive for budget-conscious patients.
FSA/HSA eligible, Novo Nordisk partnership for brand-name access, and name recognition make Hims appealing for men comfortable with the prepayment model. However, the upfront cost and 6-month commitment limit flexibility compared to month-to-month options.
Quick Comparison Table
| Provider | Rating | Tirzepatide Price | Pharmacy | Best For |
|---|---|---|---|---|
| Coreage RX | ★★★★★ | $99/mo | 503B | Best value + quality |
| WeightCare | ★★★★☆ | $275-499/mo | 503A | Tirzepatide specialist |
| Mochi Health | ★★★★☆ | $278/mo total | 503A/503B | Nutrition support |
| ReadyRx | ★★★★☆ | $399/mo | 503A | Weight loss guarantee |
| Hims | ★★★★☆ | $199/mo | 503A | Established brand |
Our Recommendation
For compounded tirzepatide, Coreage RX is the clear winner. The combination of 503B pharmacy sourcing (highest quality tier), $99/month all-inclusive pricing (lowest we've found), and comprehensive physician oversight delivers unmatched value in the compounded tirzepatide market.
At 90% less than brand-name Zepbound ($1,000+/month), Coreage makes tirzepatide's superior weight loss results accessible to patients who can't afford or don't have insurance coverage for brand-name medications.
Alternative recommendations based on priorities:
- Tirzepatide expertise: WeightCare (exclusive focus on this medication)
- Nutrition support: Mochi Health (unlimited dietitian access)
- Risk-averse: ReadyRx (5% weight loss guarantee)
- Established brand: Hims (publicly-traded, name recognition)
All five providers deliver quality compounded tirzepatide with proper medical oversight. Start with our detailed individual reviews to determine which aligns best with your budget, priorities, and health needs.
Compare All Tirzepatide Providers
Read our comprehensive reviews of every provider offering compounded tirzepatide
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